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SANTA MONICA, Calif., April 01, 2019 (GLOBE NEWSWIRE) -- Opiant Pharmaceuticals, Inc. ("Opiant") (NASDAQ: OPNT), a specialty pharmaceutical company developing medicines for addictions and drug overdose, has been awarded the second tranche of $3.0 million from the total grant of approximately $7.4 million from the National Institutes of Health’s (“NIH”) National Institute

OPNT003 is designed as a rescue medication that could be especially useful in treating overdose by high-potency synthetic opioids, such as fentanyl. SANTA MONICA, Calif., Feb. 12, 2018 (GLOBE NEWSWIRE) -- Opiant Pharmaceuticals, Inc. ("Opiant") (NASDAQ:OPNT), a specialty pharmaceutical company developing pharmacological treatments for addictions, today announced positive data from a Phase I clinical study of its product candidate OPNT003 (intranasal nalmefene), and provided an update on a meeting held February 8, 2018 with the … OPNT003, nasal nalmefene, is in development as a potent, rapid-onset, long-acting opioid antagonist for the treatment of opioid overdose. OPNT003 is designed as a rescue medication that could be especially useful in treating overdose by high-potency synthetic opioids, such as fentanyl. Study Drugs.

Opiant nalmefene

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The IN treatments were randomized while the intramuscular dose was the last treatment of all subjects. The high dose (3 mg) of nalmefene was selected based on the relative bioavailability (∼50%) OPNT003, nasal nalmefene, is in development as a potent, rapid-onset, long-acting opioid antagonist for the treatment of opioid overdose. OPNT003 is designed as a rescue medication that could be especially useful in treating overdose by high-potency synthetic opioids, such as fentanyl. “The initiation of this head-to-head study is an important step in our comprehensive development program for OPNT003, nasal nalmefene,” said Dr. Roger Crystal, President and CEO, Opiant Pharmaceuticals.

SANTA MONICA, Calif., Feb. 12, 2018 (GLOBE NEWSWIRE) -- Opiant Pharmaceuticals, Inc. ("Opiant") (NASDAQ:OPNT), a specialty pharmaceutical company developing pharmacological treatments for addictions, today announced positive data from a Phase I clinical study of its product candidate OPNT003 (intranasal nalmefene), and provided an update on a meeting held February 8, 2018 with the U.S. Food and Drug Administration (FDA) regarding its planned development program.

2020-10-30

04/05/21; Press Release. Opiant Pharmaceuticals Announces First Subjects Dosed in Study Comparing OPNT003, Nasal Nalmefene, With Nasal Naloxone · 03/31/  Prompted by an upsurge in opioid overdose deaths driven by Fentanyl and related “synthetics”, the National Institutes of Health (NIH) leadership recently. Opiant Pharmaceuticals Announces First Patient Dosed in Confirmatory Pharmacokinetic Study Assessing OPNT003, Nasal Nalmefene, for the Treatment of  Pharmacodynamic study will compare OPNT003, nasal nalmefene, with nasal naloxone in reversing the respiratory depression produced by the synthetic opioid,  TradingView UK. View live OPIANT PHARMACEUTICALS INC chart to track its stock's price action. Find market predictions, OPNT financials and market news.

We have responded to this call, and are developing an intranasal formulation of nalmefene, a more potent, longer acting opioid antagonist that is especially well-suited to treat overdose caused by synthetics.

“The potential for a faster acting, longer duration antagonist holds promise in the fight against an increasing number of opioid nalmefene solution in one nostril). Treatment D: 1.5 mg i.m. (1.5 ml of a 1.0-mg/ml nalmefene solution). The IN treatments were randomized while the intramuscular dose was the last treatment of all subjects. The high dose (3 mg) of nalmefene was selected based on the relative bioavailability (∼50%) SANTA MONICA, Calif., Dec. 14, 2020 (GLOBE NEWSWIRE) -- Opiant Pharmaceuticals, Inc. (“Opiant”) (NASDAQ: OPNT) today announced an additional commitment of up to $3.5 million from the Biomedical OPNT003, nasal nalmefene, is in development as a potent, rapid-onset, long-acting opioid antagonist for the treatment of opioid overdose.

Opiant nalmefene

22 Dec 2020 Nalmefene is used in Europe in patients with alcohol dependence but in the U.S. is better known as an antidote to opioid overdoses. The FDA  As part of Consort's deal, its units Aesica and Bespak will work with Opiant to produce a clinically pre-filled nasal spray with nalmefene, which is used in treating  Opiant Pharmaceuticals has 21 employees across 3 locations and $29.63 M in Under BARDA Contract for OPNT003 Nasal Nalmefene Development Program. 04/05/21; Press Release. Opiant Pharmaceuticals Announces First Subjects Dosed in Study Comparing OPNT003, Nasal Nalmefene, With Nasal Naloxone · 03/31/  Prompted by an upsurge in opioid overdose deaths driven by Fentanyl and related “synthetics”, the National Institutes of Health (NIH) leadership recently.
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(Mumbai, India). The IN and intramuscular solutionswereformulatedbytheVince&AssociatesClinicalResearch (VACR) pharmacy staff. Nalmefene was dissolved in 0.1 M citrate buffer, pH 4.0, for all IN formulations. Nalmefene was dissolved in OPNT003, nasal nalmefene, is in development as a potent, rapid-onset, long-acting opioid antagonist for the treatment of opioid overdose.

September 27, 2017 – Opiant CEO Dr. Roger Crystal testifies before the President’s Commission on Combating Drug Addiction and the Opioid Crisis. Press Release Opiant Pharmaceuticals Announces First Subjects Dosed in Study Comparing OPNT003, Nasal Nalmefene, With Nasal Naloxone 2019-04-08 · Opiant Pharmaceuticals Announces Publication of Clinical Pharmacokinetic Data Supporting Potential of OPNT003, Nasal Nalmefene, for Treatment of Synthetic Opioid Overdose 2020-12-14 · Opiant Pharmaceuticals Announces Additional $3.5 million Funding Under BARDA Contract for OPNT003 Nasal Nalmefene Development Program.
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OPNT003, nasal nalmefene, is in development as a potent, rapid-onset, long-acting opioid antagonist for the treatment of opioid overdose. OPNT003 is designed as a rescue medication that could be especially useful in treating overdose by high-potency synthetic opioids, such as fentanyl.

Treatment D: 1.5 mg i.m.